Current clinical trials

We have many opportunities for pet animals to participate in clinical trials. Each listing below has a quick summary plus a link to more information for each study.

chocolate lab looking at you

CAR-T cell therapy for canine CD20+ B cell lymphoma

A canine clinical trial designed to evaluate the safety and efficacy of intranodal injection of a CAR-T product for the treatment of CD20+ B-cell lymphoma

Species
Dog
Category
Cancer/Oncology
Current Status
Open and enrolling
animated gif of various dogs

COED part 2 - canine Osteosarcoma

Study to develop a reliable, minimally-invasive blood test for early detection of canine osteosarcoma.

Species
Dog
Category
Cancer/Oncology
Current Status
Ongoing but enrollment closed
close-up of a German Shepherd

Ethos PUSH01 and PUSH02

Identifying and exploring treatments for canine hemangiosarcoma

Species
Dog
Category
Cancer/Oncology
Current Status
Ongoing but enrollment closed
striped cat's face looking up

FEHI - Feline SEHI for OA

Study for cats with radiographic evidence of osteoarthritis using a novel painkiller

Species
Cat
Category
Anesthesia and pain management
Current Status
Open and enrolling
cartoon dog with harp

Lyra 1 - blood collection study for lymphoma

A minimally invasive blood sampling study to identify dogs at high risk of developing Diffuse Large B-cell Lymphoma (DLBCL). Samples must be collected at the University of Minnesota, Small Animal Hospital.

Species
Dog
Category
Cancer/Oncology
Current Status
Open and enrolling
five dogs sitting

LYRA 3 - blood collection study for lymphoma in healthy dogs at least 5 years old

This project aims to create a simple blood test that can accurately check if a healthy dog has undetected diffuse large b-cell lymphoma (DLBCL) or is at high risk of developing it. In the future, this test could be paired with targeted treatments to prevent tumors from developing. 

Species
Dog
Category
Cancer/Oncology
Current Status
Open and enrolling
black border collie

Oral Melanoma: Investigating a New Monoclonal Antibody

A double-blinded study to investigate the safety and efficacy of an investigational monoclonal antibody to aid in the treatment of malignant oral melanoma in dogs

Species
Dog
Category
Cancer/Oncology
Current Status
Open and enrolling
cartoon dog in space

ORBIT - VSV and an anti-PD-1 inhibitor for Canine Lymphoma

This study hopes to understand how a new combination immunotherapy works and to determine if it is effective in the treatment for dogs with relapsed and refractory aggressive lymphoma. There are two separate aims for the study using VSV (vesicular stomatitis virus) as a singular treatment and in combination with an anti-PD-1 inhibitor. 

Species
Dog
Category
Cancer/Oncology
Current Status
Open and enrolling
animated slides of various dogs

Shine On Continuation

Study for dogs to test eBAT prevention of cancer

Species
Dog
Category
Cancer/Oncology
Current Status
On hold
orange tabby cat sitting

The Cat MUM Study

A comparison clinical trial evaluating cat fecal microbiome and urinary metabolome in healthy cats versus stone formers and those with FIC.

Species
Cat
Category
Internal medicine
Current Status
Ongoing but enrollment closed