Clinical Investigation Center

Current Clinical Trials

We have many opportunities for pet animals to participate in clinical trials. Each listing below has a quick summary plus a link to more information for each study.

Clinical Trials Seeking Participants

Cancer (Oncology)

Cancer (Oncology)

Dogs with splenic hemangiosarcoma

Dogs with hemangiosarcoma in the spleen only and no metastasis found may be eligible for a year-long study of propranolol and doxorubicin therapy
Learn more about the PRO-DOX study

Dogs with hemangiosarcoma, other splenic lesions, other cancers and healthy young dogs - Shine On

Multi-phase study to develop effective methods for early detection and for prevention of canine hemangiosarcoma. 
Learn more about the Shine On Project

Dogs with hemangiosarcoma - compassionate care treatment with eBAT

Dogs with hemangiosarcoma in any body site, except cutaneous sites, may be eligible for treatment on a compassionate care basis with eBAT.
Learn more and apply for the study

Dogs with hemangiosarcoma (HSA) - autologous vaccine

Dogs with splenic hemangiosarcoma scheduled to have splenectomy surgery at the Veterinary Medical Center for study using vaccine made from the dog's own cells to treat the cancer.
Learn more about autologous tumor lysate vaccine for hemangiosarcoma

Dogs having limb amputation surgery (for example, due to osteosarcoma)

Study comparing bupivacaine liposome injectable suspension to standard of care for pain control during and following amputation surgery. Learn more about New nerve blocking pain control following limb amputation.

Canine oral tumors - sentinel lymph nodes

Pilot study for dogs scheduled to have CT evaluation of oral tumors.
Learn more about the sentinel lymph node study.

Brain tumor trials

Dogs with solitary brain tumors with MRI diagnosis of glioma for a twelve month trial at the Veterinary Medical Center. 
Learn more about Canine Brain Tumor Clinical Trials

Dogs having surgery for intra-abdominal tumors (adrenal & kidney masses)

Studying how the standard practice of abdominal insufflation (filling cavity with CO2 gas) affects cardiovascular systems, such as portal vein flow.
Learn more about Monitoring dogs during minimally invasive laparoscopic surgery

Canine spleen and lymph nodes - sampling for flow cytometry

Dogs having ultrasound or CT at the Veterinary Medical Center where spleen or lymph node sampling may be indicated
Learn more about Defining the flow cytometric characteristics of normal and diseased spleen and visceral lymph nodes

Animal Cancer Care and Research

Learn more about the Animal Cancer Care and Research program

Dentistry and Oral Surgery

Dentistry and Oral Surgery

Sentinel lymph nodes for canine oral tumors

Pilot study for dogs scheduled to have CT evaluation of oral tumors
Learn more about sentinel lymph node study

Dermatology

Dermatology

Dogs with superficial pyoderma

Study with cream is closed. We anticipate a new study with a new formulation soon (updated 8/9/2019)

Internal Medicine

Internal Medicine

Cats with chronic kidney disease with anemia

Clinical trial to evaluate the effectiveness a new treatment for feline anemia associated with chronic kidney disease
Read more about the Feline FREE study

Dogs with idiopathic epilepsy - food study

Clinical trial of diet and biomarker sampling. 
Learn more about Study of idiopathic epilepsy clinical cases on Purina Pro Plan veterinary diet NC for dogs

Canine spleen and lymph nodes - sampling for flow cytometry

Dogs having ultrasound or CT at the Veterinary Medical Center where spleen or lymph node sampling may be indicated
Learn more about Canine spleen and lymph nodes - sampling for flow cytometry

Orthopedics/ Surgery

Orthopedics/ Surgery

Dogs with end-stage elbow osteoarthritis (OA)

Study of safety and effectiveness of arthroscopy and external fixation device placed for 16 weeks.
Learn more about Joint distraction for dogs with end-stage elbow OA.

Dogs having limb amputation surgery

Study comparing bupivacaine liposome injectable suspension to standard of care for pain control during and following amputation surgery.
Learn more about New nerve blocking pain control following limb amputation. 

Dogs having minimally invasive laparoscopic surgery

Studying how the standard practice of abdominal insufflation (filling cavity with CO2 gas) affects cardiovascular systems, such as portal vein flow.
Learn more about Monitoring dogs during minimally invasive laparoscopic surgery