Clinical Investigation Center

Current Clinical Trials

We have many opportunities for pet animals to participate in clinical trials. Each listing below has a quick summary plus a link to more information for each study.

Clinical Trials Seeking Participants

Cancer (Oncology)

Dogs with hemangiosarcoma, other splenic lesions, other cancers and healthy young dogs - Shine On

Multi-phase study to develop effective methods for early detection and for prevention of canine hemangiosarcoma.

Learn more about the Shine On Project

Dogs with hemangiosarcoma - compassionate care treatment with eBAT

Dogs with hemangiosarcoma in any body site, except cutaneous sites, may be eligible for treatment on a compassionate care basis with eBAT.

Learn more and apply for the study

Dogs with hemangiosarcoma (HSA) - autologous vaccine

Dogs diagnosed with hemangiosarcoma of the spleen or liver scheduled for surgery at the VMC (splenectomy or lobectomy) for a clinical trial of an autologous vaccine (made from the dog's own tumor cells).

Learn more about Autologous vaccine for immunotherapy of hemangiosarcoma

Brain tumor trials

Dogs with solitary brain tumors with MRI diagnosis of glioma for a twelve month trial at the Veterinary Medical Center.

Learn more about Canine Brain Tumor Clinical Trials

Animal Cancer Care and Research

Learn more about the Animal Cancer Care and Research program

Dentistry and Oral Surgery

Sentinel lymph nodes for canine oral tumors

Pilot study for dogs scheduled to have CT evaluation of oral tumors

Learn more about sentinel lymph node study

Dermatology

Short-coated dogs with allergic skin disease

14-day study of a new topical gel.

Learn more about Safety and efficacy of a piperidine-based, reversible inhibitor of acetylcholinesterase in client-owned dogs with atopic dermatitis

Dogs with superficial pyoderma

Extended trial of ceragenin-based cream to treat canine superficial pyoderma - a randomized, double-blind, placebo controlled clinical trial

Internal Medicine

Miniature Schnauzer, Bichon Frise, Shih Tzu, Border Collie and Dachshund dogs

Study seeking these breeds with a history of calcium oxalate stones or dogs > 9 years old which have never had calcium oxalate stones

Orthopedics/ Surgery

Dogs with end-stage elbow osteoarthritis (OA)

Study of safety and effectiveness of arthroscopy and external fixation device placed for 16 weeks. Learn more about Joint distraction for dogs with end-stage elbow OA.

Dogs with osteoarthritis (OA) in elbow or knee

We are studying biomarkers in synovial fluid (joint fluid) and activity levels of dogs with OA before and after an anti-inflammatory medication is taken. Dogs with lameness due to OA and one leg worse than the others may be eligible for this 42 day study. Learn more about synovial fluid and activity study for dogs with osteoarthritis.

Dogs and Cats having tumors removed at the VMC

We are studying intraoperative lavage cytology which is routinely use in human surgical oncology to aid in post-surgical planning for patients. Dogs and cats having tumors of the thorax, abdomen or mammaries removed at the VMC may be eligible. Learn more about ILC as a predictive indicator of tumor margins.

Dogs having minimally invasive (laparoscopic) surgery

Study of effects of insufflation (filling the abdomen with CO2 gas) on particular cardiovascular systems: a prospective, randomized clinical trial. Learn more about Minimally invasive surgery monitoring.