Martin Felices , PhD
Associate Professor of Medicine
Contact
Affiliations:
Titles
Co-Director, Translation Therapy Shared Resource
Division of Hematology, Oncology, and Transplantation
Education
Ph.D., UMASS Medical School, 2008
Fellowships
Industry postdoctoral fellowship at Novartis Institutes for BioMedical Research, in Cambridge, MA, in the Developmental and Molecular Pathways group
Biography
Summary
Dr. Felices received his Ph.D. in immunology from UMASS Medical School in 2008, where his research focused on innate and adaptive immune subsets. He then pursued an industry postdoctoral fellowship at Novartis Institutes for BioMedical Research, in Cambridge, MA, in the Developmental and Molecular Pathways group where he studied signaling pathways involved in liver injury and tumorigenesis. In 2011 he joined the University of Minnesota as a T32 postdoctoral fellow in the HOT division, focusing his research on Natural Killer (NK) cell biology, prior to becoming an assistant professor. Dr. Felices' group focuses on methodologies to improve NK cell immunotherapy, with a particular focus on cytokine signaling and development NK specific biologics. In recent years Dr. Felices has been dedicating most of his effort on a Tri-specific Killer Engager (TriKE) platform to target NK cells to tumors while providing a cytokine signal.
Professional Memberships
The American Association of Immunologists, Society for Natural Immunity
Research
Research Summary
- NK cell biology (development, survival, and function)
- Cancer immunology
- Signal transduction
- Immune metabolism
- Immunotherapy Biologic
- Cytokine signaling
- Biologic design/production (bi- and tri-specifics)