Kevin Lang, PhD
Assistant Professor, Department of Veterinary and Biomedical Sciences
Titles
Assistant Professor, Department of Veterinary and Biomedical Sciences
Faculty, Microbiology, Immunology and Cancer Biology (MICaB) Ph.D. Graduate Program
Faculty, Masonic Cancer Center
Education
PhD, College of Veterinary Medicine, University of Minnesota
B.S. Microbiology, University of Minnesota
Fellowships
Postdoctoral Fellow, Vanderbilt University
Biography
Summary
The Lang Lab is focused on understanding how core biological processes, such as DNA replication, transcription, and translation, are affected during host-pathogen interactions. We use a multi-disciplinary approach including genetics, biochemistry, cell biology, proteomics, and genomics to answer fundamental questions about the biology of living cells.
Expertise
- Host-pathogen interactions
- Bacteriology
- DNA replication
- DNA repair
Awards & recognition
- Richard Armstrong Faculty Transition Award, Department of Biochemistry, Vanderbilt University, 2021
- NIH F32 Ruth L. Kirschstein Postdoctoral Fellowship, 2019-2020
- NIH T32 Bacterial Pathogenesis Training Grant, 2018
- USDA AFRI NIFA Fellowship, 2013-2015
Publications
Selected publications
For a complete list of publications, please visit Google Scholar
- Kevin S. Lang and H. Merrikh. (2021) Topological stress is responsible for the detrimental outcomes of head-on replication-transcription conflicts. Cell Reports 34(9), 108797.
- D. Ma, Z. Wang, C.N. Merrikh, Kevin S. Lang, P. Lu, X. Li, H. Merrikh, Z. Rao, and W. Xu. (2018) Crystal structure of a membrane-bound O-acyltransferase. Nature 562(7726):286-290
- Kevin S. Lang and H. Merrikh. (2018) The clash of macromolecular titans: replication-transcription conflicts in bacteria. Annual reviews Microbiology 72: 71-88.
- Kevin S. Lang*, A.N. Hall*, C.N. Merrikh, M. Ragheb H. Tabakh, A.J. Pollack, J.J. Woodward, J.E. Dreifus and H. Merrikh. (2017) Replication-transcription conflicts generate R-loops that orchestrate bacterial stress survival and pathogenesis. Cell 170(4): 787-799.e18. *Equal contribution. F1000 recommended.