Alonso Guedes, DVM, MS, PhD, Dipl. ACVA

Associate Professor of Anesthesia, Veterinary Clinical Sciences, Interim Associate Dean for Research


Anesthesia Resident, University of Minnesota

PhD, University of Minnesota

DVM, University of Santa Maria, Brazil

MS, University of Santa Maria, Brazil

Licensures and Certifications

Diplomate American College of Veterinary Anesthesia and Analgesia

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Dr. Alonso Guedes is a DVM, PhD and board certified veterinary anesthesiologist interested in understanding how calcium and lipid signaling are involved in chronic disease biology. Diseases of interest include osteoarthritis, laminitis and asthma.


Veterinary Anesthesia and Pain Medicine


Research summary/interests

Our laboratory is invested in the discovery of novel and actionable targets for the treatment of chronic painful conditions such as osteoarthritis, laminitis and asthma, using basic and translational models. Current work focuses on two target proteins, CD38 (calcium signaling) and sEH (lipid metabolism).


Selected publications

  • Guedes AGP, Aristizabal F, Sole A, Adedeji A, Brosnan R, Knych H, Yang J, Hwang SH, Morisseau C, Hammock BD. Pharmacokinetics and antinociceptive effects of the soluble epoxide hydrolase inhibitor t-TUCB in horses with experimentally induced radiocarpal synovitis. J Vet Pharmacol Ther. 2018;41(2):230-8. doi: 10.1111/jvp.12463. PubMed PMID: 29067696.
  • Guedes AGP, Meadows JM, Pypendop BH, Johnson EG, Zaffarano B. Assessment of the effects of gabapentin on activity levels and owner-perceived mobility impairment and quality of life in osteoarthritic geriatric cats. J Am Vet Med Assoc. 2018;253(5):579-85. Epub Accepted for publication. doi: 10.2460/javma.253.5.579. PubMed PMID: 30110208.
  • Guedes A, Galuppo L, Hood D, Hwang SH, Morisseau C, Hammock BD. Soluble epoxide hydrolase activity and pharmacologic inhibition in horses with chronic severe laminitis. Equine Vet J. 2017;49(3):345-51. Epub 2016/06/25. doi: 10.1111/evj.12603. PubMed PMID: 27338788; PMCID: PMC5580818.


Clinical interests

  • Veterinary Anesthesiology
  • Pain Medicine
  • Osteoarthritis
  • Laminitis