Available Canine Brain Tumor Trials

A circle of doctors and nurses in the middle of surgery.

Investigating the safety and efficacy of simvastatin infusions in pet dogs with high-grade gliomas

Study Sponsor

Da Zen Theranostics

About

This trial focuses on providing a drug, simvastatin, to pet dogs with high-grade glioma to determine if it prolongs survival. Tumors are removed surgically. Then, enrolled dogs receive intravenous (IV) infusions (drips) of the drug on a weekly, then biweekly, basis. Every 10 weeks, MRIs are performed to monitor treatment response.

Enrollment requirements

All dogs with MRI-confirmed gliomas are eligible for enrollment in this trial. Dogs must be amenable to having intravenous catheters placed for drug delivery. Prior to enrollment, dogs must be screened for any evidence of cancer in their thorax (chest) or abdomen.

Covered costs

  • All costs associated with surgery, post-operative MRI, post-operative care, and infusions are covered by the study
  • Clients must pay for pre-enrollment thoracic (chest) and abdominal radiographs (X-rays), and for the MRI that is performed to diagnose their dog's brain tumor