Newly funded: Targeting virus assembly to inhibit SARS-CoV-2 infection and COVID-19

August 17, 2020
In order for the SARS-CoV-2 to infect humans and cause COVID-19 disease, it must be able to produce more progeny viruses in the infected cells. This process of viral assembly depends on coordinated interactions between the different viral proteins. Since this is an important process that is required for viral infection and disease pathogenesis, Postdoctoral Associate Md Mizanur Rahman, MS, PhD, in the laboratory of Hinh Ly, MA, PhD, and Yuying Liang, MS, PhD, hypothesizes that disrupting the essential viral protein-protein interactions with antiviral drugs presents a tremendous opportunity to cripple virus replication in order to ameliorate COVID-19. This project is funded by the UMN COVID-19 Rapid Response Research Grants program from August 15, 2020, to August 14, 2021.