LYRA 3 - blood collection study for lymphoma in healthy dogs at least 5 years old

five dogs sitting
Principal Investigator
Jaime Modiano, VMD, PhD
Perlman Professor of Oncology and Comparative Medicine, Veterinary Clinical Sciences
Caitlin Feiock, DVM
Assistant Professor, Veterinary Clinical Sciences
Co-investigator

Aaron Sarver, PhD
Research Assistant Professor - Institute of Health Informatics
Masonic Cancer Research Center
[email protected]

Amy Treeful, PhD, MS
Postdoctoral Associate - Modiano Lab
Masonic Cancer Research Center
[email protected]

Contact

Mitzi Lewellen 
[email protected]
612-626-8452

Amber Winter, CVT (contact for patients being seen at the University of MN, Vet Med Center)
Research Professional 2
[email protected]
612-624-1352

Category:
Cancer/Oncology
Species:
Dog
Current status: Open and enrolling

Study title

Early Detection, Risk Stratification, and Strategic Prevention of Canine Lymphoma - Part III - Healthy Community Dog Enrollment (Validation Set)

Purpose of study

This project aims to create a reliable blood test kit that can identify dogs at high risk of developing DLBCL. This test could later be paired with treatments to stop DLBCL from developing before it starts; however, no treatments or preventatives will be offered at this stage of the project. 

Eligibility criteria

Dogs should be:

  • Be at least 5 years old
  • Any breed, gender, or neuter status
  • Have no history of any cancer
  • Be currently healthy - attested by a veterinary health professional with a brief exam and history concluding good health
  • Live in the contiguous 48 states of the U.S.

 

Owners agree to:

  • Schedule the sample collection appointment with their vet after being contacted by the project team with available dates
  • Complete all portions of the informed consent
  • Complete emailed follow-up health surveys every 6 months for the life of their enrolled dog
  • Submit additional blood samples for re-testing according to the study guidelines (only if specifically requested by the project team)

Procedures

Upon enrollment, your veterinary clinic will receive a kit with instructions and blood collection tubes to collect a total of up to 15mls of blood (about 3 tsp). No spinning of blood samples is required at this time. A follow-up sample may be requested from a percentage of enrolled dogs at a later date; follow-up samples may include spun samples. 

Costs

The study covers the costs of the kit and shipping both ways. Owners are responsible for all costs associated with the office visits and procedures.